International Journal of Hematology and Oncology
2024, Vol 34, Num 2 Page(s): 102-112
| Back | Table of Contents | PDF | Mail to Author | |
The Relationship Between Microplastics and Nanoplastics with Cancer: An Emerging Health Concern
Yigit YAZARKAN1, Gamze SONMEZ1, Ates KUTAY TENEKECI1, Eda Ayse AKSOY2, Ibrahim Halil GULLU3
1Hacettepe University, Faculty of Medicine, Sixth-year Medical Student
2Hacettepe University, Faculty of Pharmacy, Department of Basic Pharmaceutical Sciences
3Hacettepe University, Cancer Institute, Department of Medical Oncology
Keywords: Microplastics, Nanoplastics, Oncogenesis, Cancers
There is an increasing apprehension surrounding the potential health implications associated with prolonged exposure to environmental micro- and nano-plastics (MNPLs) on the human population. Microplastics pose significant threats to both aquatic and terrestrial ecosystems, entering water bodies through various pathways and accumulating in sediments. Additionally, they infiltrate terrestrial environments, spreading contamination through air, water, and soil, impacting soil health and potentially entering the food chain. Likewise, humans encounter microplastics through diverse exposure routes. Studies have demonstrated that multiple substances involved in oncogenetic pathways can trigger carcinogenesis in the human body, leading to various cancers such a colorectal, liver, lung, skin, breast, biliary tract, leukemia, and pancreatic cancers. In this review, we examine the literature highlighting this emerging health issue.
Yigit YAZARKAN1, Gamze SONMEZ1, Ates KUTAY TENEKECI1, Eda Ayse AKSOY2, Ibrahim Halil GULLU3
1Hacettepe University, Faculty of Medicine, Sixth-year Medical Student
2Hacettepe University, Faculty of Pharmacy, Department of Basic Pharmaceutical Sciences
3Hacettepe University, Cancer Institute, Department of Medical Oncology
Keywords: Microplastics, Nanoplastics, Oncogenesis, Cancers
There is an increasing apprehension surrounding the potential health implications associated with prolonged exposure to environmental micro- and nano-plastics (MNPLs) on the human population. Microplastics pose significant threats to both aquatic and terrestrial ecosystems, entering water bodies through various pathways and accumulating in sediments. Additionally, they infiltrate terrestrial environments, spreading contamination through air, water, and soil, impacting soil health and potentially entering the food chain. Likewise, humans encounter microplastics through diverse exposure routes. Studies have demonstrated that multiple substances involved in oncogenetic pathways can trigger carcinogenesis in the human body, leading to various cancers such a colorectal, liver, lung, skin, breast, biliary tract, leukemia, and pancreatic cancers. In this review, we examine the literature highlighting this emerging health issue.
| Back | Table of Contents | PDF | Mail to Author | |