International Journal of Hematology and Oncology 2024, Vol 34, Num 1 Page(s): 045-053
Comparison of Tomotherapy, Volumetric Arc Therapy and Three-Dimensional Conformal Radiotherapy Planning Techniques with Dosimetric Parameters in Pediatric Craniospinal Radiotherapy


1Inonu University, Turgut Ozal Medicine Center, Department of Radiation Oncology
2University of Health Sciences, Gulhane Faculty of Medicine, Department of Radiation Oncology

Keywords: Dosimetric Comparison, Pediatric Craniospinal, Radiotherapy, Treatment planinng
In present study, the comparison results of craniospinal radiotherapy plans using three different planning techniques including helical tomotherapy (HT), volumetric arc therapy (VMAT) and three-dimensional conformal radiotherapy (3D-CRT) were evaluat-ed in pediatric patients diagnosed with medulloblastoma depending on dosimetric parame-ters. Ten pediatric patients with medulloblastoma were planned with 3 techniques. Standard-risk medulloblastoma treatment doses of 23.4 Gy in the craniospi-nal region and 54 Gy in the posterior fossa region were used. When comparing treatment plans, doses of PTV, V95%, maximum PTV dose, homogeneity index (HI) conformity index (CI) criteria were taken into account. When the dosimetric results of PTV are examined; It has been seen that all plans meet the desired criteria, but the target volume coverage of tomotherapy is superior in do-simetric results compared to VMAT and 3D-CRT due to its ability to irradiate at once without field intersection (p< 0.003). It was found that the HI results of the tomo-therapy plans and the CI results of the VMAT plans were closer to the criteria expected from the ideal plan. Target max dose were reduced with for tomotherapy and vmat compared to 3DCRT. When all treatment modalities are compared, it can be said that modern radio-therapy techniques may be preferred in Medulloblastoma radiotherapy because they have sufficient target volume coverage, good dose homogeneity and low maximum doses.