International Journal of Hematology and Oncology 2019, Vol 29, Num 4 Page(s): 246-255
Quality of Life in Endometrial Cancer Survivors: A 10-year Experience from a Cancer Center in Slovakia

Erik LAJTMAN

The Constantine Philosopher University in Nitra, Department of Gynecology and Obstetrics, Faculty Hospital, Nitra, SLOVAKIA

Keywords: Quality of life, Endometrial cancer, Obesity, Lymphoedema
The aim of this study is to evaluate the effect of body mass index (BMI) on quality of life among endometrial cancer survivors. Women diagnosed with endometrioid endometrial cancer at the Slovakian university hospital between January 2010 and December 2018 were identified. Quality of life was measured using the EORTC (European Organisation for Research and Treatment of Cancer) quality of life questionnaires (QLQ-C30 and QLQ-EN24). Univariate and multiple regression analyses were used to determine associations between BMI and quality-of-life outcome variables. 390 women diagnosed with endometrial cancer were invited to participate, 337 (95.2%) completed the questionnaire. Of all women, 131 (38.8%) were pre-obese, 111 (32.9%) were obese and 29 (8.6%) were morbidly obese. Women with increased BMI experienced poorer physical, emotional and social functioning. Obese and morbid obese women had significantly more lymphoedema (59% v. 41%, p=0.048) and dyspnea (73% v. 27%, p= 0.029), and experienced more fatigue (68% v, 32%, p= 0.036) and pain (65% v. 35%, p= 0.041). Obesity and morbid obesity was associated with poorer quality of life in endometrial cancer survivors. Lifestyle changes (e.g., dietary interventions, physical activity) might reduce obesity and improve quality of life among endometrial cancer survivors. Future studies are needed.