International Journal of Hematology and Oncology
2023, Vol 33, Num 4 Page(s): 109-116
IMPORTANCE OF BIPHOSPHONATES IN THE TREATMENT OF BREAST CANCER
UĞUR COŞKUN1, YEŞİM YILDIRIM1, NAZAN GÜNEL1
Gazi Üniversitesi Tıp Fakültesi Medikal Onkoloji BD, ANKARA
Keywords: breast cancer, bone metastases, bisphosphonates
Breast cancer is the most common cancer in the women. Bone metastases are found approximately 65% of advanced breast cancer patients. Bisphosphonates are used in the breast cancer patients with bone metastases for palliation of pain and prevention of skeletal complications. Many studies indicate that progression of bone metastases are prevented by bisphosphonates. Mechanism of action, types and efficacy of bisphosphonates are reviewed here. More potent and new bisphosphonates may replace the old ones in the future.
UĞUR COŞKUN1, YEŞİM YILDIRIM1, NAZAN GÜNEL1
Gazi Üniversitesi Tıp Fakültesi Medikal Onkoloji BD, ANKARA
Keywords: breast cancer, bone metastases, bisphosphonates
Breast cancer is the most common cancer in the women. Bone metastases are found approximately 65% of advanced breast cancer patients. Bisphosphonates are used in the breast cancer patients with bone metastases for palliation of pain and prevention of skeletal complications. Many studies indicate that progression of bone metastases are prevented by bisphosphonates. Mechanism of action, types and efficacy of bisphosphonates are reviewed here. More potent and new bisphosphonates may replace the old ones in the future.