International Journal of Hematology and Oncology 2023, Vol 33, Num 4 Page(s): 042-045
Synchronous Squamous Cell Lung Carcinoma and Rectum Adenocarcinoma: Case Report

A. Osman KAYA1, Ramazan YILDIZ1, Banu ÖZTÜRK1, Emel YAMAN1, Gonca BARIT2, Uğur COŞKUN1, Aytuğ ÜNER1, Mustafa BENEKLİ1, Deniz YAMAÇ1, Süleyman BÜYÜKBERBER1

1Gazi Üniversitesi Tıp Fakültesi, Tıbbi Onkoloji Bilim Dalı, ANKARA
2Gazi Üniversitesi Tıp Fakültesi, Patoloji Anabilim Dalı, ANKARA

Keywords: Synchronous, Squamous cell lung cancer, Rectosigmoid adenocarcinoma, Leukocytosis, Paraneoplastic syndrome
A 67-year old man patient with dispnea, weakness at the right arm and rectal bleeding, was admitted to our hospital with a nodular large mass in the right upper lung field on chest X-ray. Colonoscopy revealed an ulcerovegetan mass in the rectosigmoid region. Colonoscopic biopsy was performed and the histopathological diagnosis of a specimen was evaluated as adenocarcinoma. Chest computed tomography revealed an 8 cm mass lesion with heterogenous density in the right upper lung field. Transbronchial biopsy of the specimen revealed squamous cell carcinoma. The patient was diagnosed as synchronous squamous cell lung cancer and rectum adenocarcinoma, who was treated with only supportive therapy due to his poor performance status. Complete blood count showed excessive leukocytosis that was evaluated due to paraneoplastic syndrome. He died shortly after diagnosis. Synchronous lung and rectum cancers together with paraneoplastic leukocytosis was rarely reported in the literature.