International Journal of Hematology and Oncology
2023, Vol 33, Num 4 Page(s): 189-195
REPORT OF 9 CASES WITH PRIMARY PENILE CANCER: A RETROSPECTIVE ANALYSIS AND REVIEW OF THE LITERATURE
FERHAT BERKMEN1, SİNAN BAŞAY1, A. İHSAN ARIK1, ALİ AYYILDIZ1, BEDRETTİN SEÇKİN1, A. FUAT PEKER1
Ankara Onkoloji Eğitim-Araştırma Hastanesi Üroloji Kliniği
Keywords: penile cancer, diagnosis, staging, classification, treatment
Cancer of the penis is a rare disease in Turkey. However, it represents a significant health problem with an incidence of 10-20% in some countries. It usually presents in the sixth decade of life. The abscence of circumcision, aging and poor hygiene are the main risk factors. Although the specific carcinogenes in smegma remains unidentified, circumcision eradicates its carcinogenic potential. Over 95% of penile carcinomas are histologically squamous cell carcinoma. Metastatic tumors of the penis often originates as cancers of the bladder, prostate, kidney and rectosigmoid primaries. Most urologists, unless practicing at a major oncology center will infrequently treat a patient with penile carcinoma. Additionally, penis tumor is less common than other genitourinary malignancies and represents formidable challenges. From 1985 to 1999, 18 patients (9 primary and 9 metastatic cases), with a diagnosis of penile carcinoma, were treated at our clinic. In this study, our experience in 9 patients with a diagnosis of primary penile carcinoma; 7 cases of squamous cell carcinoma and two patients with Kaposi sarcoma limited to glans penis is presented.
FERHAT BERKMEN1, SİNAN BAŞAY1, A. İHSAN ARIK1, ALİ AYYILDIZ1, BEDRETTİN SEÇKİN1, A. FUAT PEKER1
Ankara Onkoloji Eğitim-Araştırma Hastanesi Üroloji Kliniği
Keywords: penile cancer, diagnosis, staging, classification, treatment
Cancer of the penis is a rare disease in Turkey. However, it represents a significant health problem with an incidence of 10-20% in some countries. It usually presents in the sixth decade of life. The abscence of circumcision, aging and poor hygiene are the main risk factors. Although the specific carcinogenes in smegma remains unidentified, circumcision eradicates its carcinogenic potential. Over 95% of penile carcinomas are histologically squamous cell carcinoma. Metastatic tumors of the penis often originates as cancers of the bladder, prostate, kidney and rectosigmoid primaries. Most urologists, unless practicing at a major oncology center will infrequently treat a patient with penile carcinoma. Additionally, penis tumor is less common than other genitourinary malignancies and represents formidable challenges. From 1985 to 1999, 18 patients (9 primary and 9 metastatic cases), with a diagnosis of penile carcinoma, were treated at our clinic. In this study, our experience in 9 patients with a diagnosis of primary penile carcinoma; 7 cases of squamous cell carcinoma and two patients with Kaposi sarcoma limited to glans penis is presented.